秦宁波,男,硕士生导师,1987年1月出生。2017年毕业于沈阳药科大学中药学院药学(天然药物化学)专业,获理学博士学位。
1、主要学术研究方向:海洋食品成分对肠道微生态的调控机制研究;食品成分的高值化开发利用。
2、招收硕士生所在一级学科:食品科学与工程
3、目前承担主要课程:本科生课程:食品分析、食品感官评定、海洋药物资源开发利用
研究生课程:现代分离分析技术、天然产物化学
4、指导硕士研究生情况:毕业1名,在读1名。
5、承担科研项目情况:参与国家重点研发计划项目1项,参与国家自然科学基金项目1项,参与省市级项目1项,主持省市级项目1项。发表学术论文17篇,其中第一作者或通讯作者发表SCI收录论文7篇,以第一发明人申请国家专利2项。
1. 2019-2022,辽宁省博士启动基金“肠道菌群持续性紊乱对高白鲑鱼油和高脂膳食循环改变的响应机制”,项目号:2019-BS-019(主持)。
2. 2021-2025,国家自然科学基金面上项目“岩藻多糖调节拟杆菌多糖利用策略改善肠道微生态平衡的研究”,项目号:32072226(参与)
3. 2018-2021,国家重点研发计划课题“特殊食品中效应物质的高通量检测方法研究”,项目号:2018YFC1602306(参与)
4. 2019-2021,辽宁省“兴辽英才计划”项目“天然产物抗副溶血性弧菌感染的效应及机制研究”,项目号:XLYC1807220(参与)
6、主要代表作:
1.Ningbo Qin*, Guoku Song, Xiaomeng Ren, Lihua Zhang, Jingzhu Gao, Xiaodong Xia*and Beiwei Zhu. Fish oil extracted from Coregonus peled improves obesephenotype and changes gut microbiota in a high-fat diet-induced mouse model ofrecurrent obesity. Food & Function, 2020, 11, 6158-6169. (SCI,IF:4.171)
2.Yu Cao, Hongli Liu, Ningbo Qin, Xiaomeng Ren, Beiwei Zhu, Xiaodong Xia*. Impactof food additives on the composition and function of gut microbiota: A review.Trends in Food Science & Technology, 2020, 99, 295-310. (SCI,IF:11.077)
3.Xu Hu#, Ningbo Qin#, Jingjing Xue, Siqi Li, Xiaofang Huang, Jianan Sun, FanxingXu*, Zhanlin Li, Dahong Li*, Huiming Hua*. Dehydrodiconiferyl alcohol fromsilybum marianum (L.) gaertn accelerates wound healing via inactivating NF-κBpathways in macrophages. Journal of Pharmacy and Pharmacology. 2019, 72,305-317. (SCI,IF: 2.39)
4.Ningbo Qin, Tatsunori Sasaki, Wei Li*, Jian Wang, Xiangyu Zhang, Dahong Li,Zhanlin Li, Maosheng Cheng, Huiming Hua*, Kazuo Koike. Identification offlavonolignans from Silybum marianum seeds as allosteric protein tyrosinephosphatase 1B inhibitors. Journal of Enzyme Inhibition and MedicinalChemistry. 2018, 33, 1283-1291. (SCI,IF: 4.027)
5.Can Xu, Ningbo Qin, Chunyan Yan*, Shumei Wang*. Iaolation, purification,characterization and bioactivities of a glucan from the root of Puerarialobata. Food & Function, 2018, 9, 2644-2652. (SCI,IF:3.241)
6.Ningbo Qin, Xu Hu, Shengge Li, Jian Wang, Zhanlin Li, Dahong Li*, Fanxing Xu*,Ming Gao, Huiming Hua*. Hypoglycemic effect of Silychristin A from Silybummarianum fruit via protecting pancreatic islet β cells from oxidative damageand inhibiting α-glucosidase activity in vitro and in rats with Type 1diabetes. Journal of Functional Foods, 2017, 38, 168-179. (SCI,IF:3.47)
7.Ningbo Qin, Shengge Li, Xueyuang Yang, Chi Gong, Xiang-yu Zhang, Jian Wang*,Da-hong Li, Yuan-qiang Guo, Zhan-lin Li, Hui-ming Hua*. Bioactive terpenoidsfrom Silybum marianum and their supression on NO release in LPS-induced BV-2cells and interaction with iNOS. Bioorganic & Medicinal Chemistry Letters,2017, 27, 2161-2165. (SCI,IF: 2.442)
8.Ningbo Qin, Cuicui Jia, Jun Xu, Dahong Li, Fanxing Xu, Jiao Bai, Zhanlin Li*,Huiming Hua*. New amides from seeds of Silybum marianum with potentialantioxidant and antidiabetic activities. Fitoterapia, 2017, 119, 83-89. (SCI,IF;2.642)
9.Chunmei Sai, Ningbo Qin, Cuicui Jia, Dahong Li, Kaibo Wang, Yu-hu Pei, JiaoBai, Zhanlin Li*, Huiming Hua*. Macleayine, a new alkaloid from Macleayacordata. Chinese Chemical Letters, 2016, 27, 1717-1720. (SCI,IF:4.632)
10.Ningbo Qin, Aoli Wang, Dahong Li, Kaibo Wang, Bin Lin, Zhanlin Li*, HuimingHua*. Cytotoxic clerodane furanoditerpenoids from the root of Tinosporasagittata. Phytochemistry Letters, 2015, 12, 173-176. (SCI,IF:1.418)
11.秦宁波, 李达翃,李占林,华会明*. 圆二色谱法在黄酮木脂素绝对构型测定中的应用进展[J]. 国际药学研究杂志,2015, 42 (6): 794-801.
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