杨义,博士,教授,硕士生导师。中国科学院新疆理化技术研究所和美国国立卫生院(NIH)国家心脏肺与血液研究所(NHLBI)联合培养博士研究生,2010年7月取得博士学位。先后在中国科学院大连化学物理研究所和中国科学院新疆理化技术研究所工作,2013年5月调入大连工业大学。2016年12月-2017年12月,美国国立卫生院(NIH)国家生物医学影像与生物工程研究所(NIBIB)访问学者。担任国家自然基金函评专家和第九届天然化合物化学国际研讨会(英文国际会议)的学术委员会委员。
E-mail: yangy@dlpu.edu.cn
一. 主要学术研究方向:功能生物分子;高效分析分离新方法和新技术;高效活性筛选方法
二. 招收硕士生所在一级学科:化学工程与技术、化学、材料与化工
三. 目前承担主要课程:《有机化学》《有机化学实验》
四. 指导硕士研究生情况:培养和协助培养研究生中,已毕业13名,在读5名。其中,6人获国家奖学金。所有毕业研究生均已发表一作SCI论文。
五. 出版著作情况:
1. 参编《有机化学学习指南》(化学工业出版社)。
2. Zhaosheng Liu, Yanping Huang, Yi Yang, Molecularly Imprinted Polymers as Advanced Drug Delivery Systems-Synthesis, Character and Application, Springer Nature, 2021.
六. 承担科研项目情况:主持国家自然科学基金青年基金(20902106)、科技部973前期项目“重大疾病治疗药物药理学研究”子课题(2011CB512013)、中国科学院西部之光博士项目(XBBS201011)、大连工业大学青年基金项目(QNJJ201301)、辽宁省教育厅科学研究一般项目(L2013219)、辽宁省自然基金项目优秀人才培育专题(2014026015)、辽宁省教育厅科学技术研究项目(2017J028)、辽宁省自然基金面上项目(2019-MS-018)。作为主要研究人员,参与国家自然基金重点项目、国家自然基金面上项目、科技部973前期项目等各类科研项目20+项。
七. 发表论文和专利情况:发表SCI论文100+篇,第一/通讯累计IF260+(中科一区16篇),H指数25。参与授权专利19项。Industrial Crops & Products, Food Research International, International Journal of Biological Macromolecules,Separation & Purification Technology, Food Chemistry, Talanta, Phytomedicine, Critical Reviews in Biotechnology, Journal of Chromatography A等40+种SCI杂志的评审专家。
中科一区论文
1. Artificial
antibody-antigen-directed immobilization of α-amylase to hydrolyze starch for
cascade reduction of 2-nitro-4-methylphenol to 2-amino-4-methylphenol, International Journal of Biological Macromolecules, 2024, 277, 134116. (通讯)
2. Artificial
antibody-antigen-directed immobilization of lipase for consecutive catalytic
synthesis of ester: Benzyl acetate case study, Bioresource Technology,
2024, 403, 130894. (第一)
3. Biomimetic immobilization
of α-glucosidase inspired by antibody-antigen specific recognition for
catalytic preparation of 4-methylumbelliferone, International Journal of Biological Macromolecules, 2024, 268, 131697.
(通讯)
4. Near-infrared
photodynamic and photothermal co-therapy based on organic small molecular dyes, Journal of Nanobiotechnology, 2023, 21, 348. (通讯)
5. Thermodynamics, kinetics and structure-activity
relationship of hydroxyanthraquinones scavenging free radicals, Food
Bioscience, 2023, 53, 102705. (通讯)
6. Immobilized enzyme for
screening and identification of anti-diabetic components from natural products
by ligand fishing, Critical Reviews in Biotechnology, 2023, 43(2), 242-257.(通讯,中科二区)
7. Lipase immobilization on
multi-walled carbon nanotubes used as a target fishing tool and followed by
molecular docking technique to analyze lipase inhibitor from Robinia pseudoacacia L., Industrial Crops &
Product, 2022,
178, 114645. (通讯)
8. An efficient method based on an inhibitor-enzyme
complex to screen an active compound against lipase from Toona sinensis, Food & Function, 2021, 12,
10806-10812. (通讯)
9. Rapid screening and
separation of active compounds against α-amylase from Toona sinensis by ligand fishing and high-speed counter-current
chromatography, International Journal of Biological Macromolecules, 2021, 174: 270-277.
(通讯)
10. Different behavior of
bovine serum albumin as foaming agent in foam enrichment of Rhodamine 6Gand Evans Blue, Separation
and Purification Technology, 2020, 252: 117509. (第一)
11. Elution-extrusion and back-extrusion counter-current chromatography
using three-phase solvent system for separation of organic dye mixture, Separation and Purification Technology, 2020,
248: 117024. (第一)
12. Enzyme reaction-guided identification of active components from the flowers of Sophora japonica var. violacea, Food & Function, 2020, 11, 4356-4362. (通讯)
13. Optimization
of fungi co-fermentation for improving anthraquinone contents and antioxidant
activity using artificial neural networks, Food Chemistry, 2020, 313: 126138. (通讯)
14. GC-MS profiling, bioactivities and In silico theoretical explanation
of cone oil from Pinus
thunbergii Parl., Industrial Crops & Products, 2019, 141: 111765. (第一)
15. Comprehensive
separation of major compositions from Sophora
japonica var. violacea by counter-current chromatography using a
liquid-liquid extraction strategy, Industrial Crops & Products, 2018,
124: 363-368. (通讯)
16. In
silico-assisted identification of α-amylase inhibitor from the needle oil of Pinus tabulaeformis Carr., Industrial
Crops & Products, 2018, 111: 360-363. (通讯)
17. Characterization
of active compounds from Gracilaria
lemaneiformis inhibiting the protein tyrosine phosphatase 1B activity, Food & Function, 2017, 8(9):
3271-3275. (通讯)
18. Screening
of the potential α-amylase inhibitor in essential oil from Cedrus deodara cones, Industrial Crops & Products, 2017,
103: 251-256. (通讯)
19. An
approach based upon the consecutive separation and the economical two-phase
solvent system preparation using UNIFAC mathematical model for increasing the
yield of high-speed counter-current chromatography, Separation and Purification
Technology, 2016, 162: 142-147. (通讯)
20. Large-scale
separation of ricinine from a by-product of Ricinus
communis L. by pH-zone-refining counter-current chromatography, Industrial Crops
and Products, 2013,
49: 160-163. (通讯)
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